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Success in research demands creativity, the ability to think critically and mastery of technical skills. Although it is often said that one “cannot teach creativity,” it certainly can be encouraged and rewarded. As for critical thinking and technical skills, these are acquired through a carefully structured curriculum that emphasizes learning from original research papers and hands-on laboratory experience rather than summaries usually found in textbooks. In all cases, the training program in our graduate program at is highly individualized so that each student has the freedom to pursue their own scientific interests with respect to their unique academic history. There is, however, a fundamental base of knowledge in the life sciences (cell biology, biochemistry, systems physiology) that provides a strong foundation for advanced study. Course work in these areas constitutes the core curriculum.